The Hampton Inn and Suites Watertown is nestled in the heart of the Glacial Lakes Region of northeastern South Dakota. Our Watertown hotel is conveniently located at the junction of Interstate 29 and Highway 212. Our hotel is minutes from Watertown’s historic uptown. Guests enjoy our spacious rooms or suites with free breakfast and Wi-Fi, and access to the fitness center and indoor pool. Let our friendly staff and comfortable accommodations make the best of your stay in Watertown.