The Chamberlain-Oacoma Area Chamber of Commerce/CVB is your one-stop information service for south central South Dakota. Chamberlain and Oacoma are located at the crossroads of Interstate 90 and the majestic Missouri River. Contact us for information about our area, activity guides and conference packets. We will assist you with planning your visit to our area. Our office hours are 8 a.m.-5 p.m., Monday through Friday.